直肠癌的现代治疗 Modern Management of Cancer of the Rectum mobi 下载 网盘 caj lrf pdf txt 阿里云

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内容简介:
addresses such topics as epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and trans*** endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; togethe***ith new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.
书籍目录:
List of Contributors
Introduction
1 Evolution of the Surgical Management of Rectal Cancer
Introduction
Perineal Approach
Trans*** Excision
Transsacral Resection
Abdominosacral Resection
Abdominoperineal Resection
Abdomino*** Approach
Anterior Resection
The Present
References
2 Pathology and Staging
Introduction
Resection Specimen
Total Mesorectal Excision
Histological Features of Rectal Cancer and Their Prognostic Significance
Histological Type
Tumour Differentiation
Invasive Growth Pattern and Peritumoral
Lvmphocytic Infiltration
Completeness ofExcision
Serosal Involvement
LYmph Node Metastases
ExtramuralVascular Invasion
SurgicalResectionMargins andLocalRecurrence
Local Recurrence
Longitudinal Resection Margin
Circumferential Resection Margin
Staging ofRectal Cancer
Staging Systems Currently in Existence
DukesStaging
TNM Staging System
DukesStagingVersus TNM
Role of Pathology in Assessing the Quality of Rectal Cancer Surgery
Quality of Preoperative Imaging and Pathology Reporting,and the
Use ofReporting Proformas
Conclusi***
References
3 Genetics,Screening and Chemoprevention
Introduction
Genetics
Tumor Suppressor Genes
MMR Genes
Oncogenes
Screening
Average Risk
Moderate Risk
Increased Risk
Chemoprevention
NSAIDS
Calcium
AntioxidantVitamins
Circumin
Perillyl Alcoh01
Oltipraz
Selenium
References
4 The Role of Imaging in the Diagnosis and Staging of Primary and Recurrent Rectal Cancer
Introductionl
Diagnostic Imaging in the Staging of Primary Rectal CancerI
Clinical Evaluation
Contrast Examinati***
Endorectal Ultrasound
Computed Tomography
Magnetic Resonance Imaging
Positron Emission Tomography
Radioimmunoscintigraphy
Diagnostic Imaging in the Dia19nosis and Staging of Recurrent Rectal Cancer
Ultrasound Techniques
Computed Tomography
Magnetic Resonance Imaging
Positron Emission Tomography and Immunoscintigraphy
Conclusi***
References
5 Ne0adjuvant Therapy
Introduction
Preoperative Therapy
Rationale
Predictors ofResp***etoPreoperativeTherapy
Results ofPreoperative Therapy
Intensive ShortCourse PreoperativeRadiation
Sphincter Preservation with Preoperative Radiation
Is Aduvant Therapy Necessary in Patients Undergoing a Total Mesorectal
Resection7
Investigational Approaches
Altered Radiation Fractionation Schemes
New Chemothe***utic Agents
6 Restorative Procedures
7 Abdominoperineal Resection
8 Total Mesorectal Excision with Autonomic Nerve Preservation: "Optimized Surgery"
9 Laparoscopic Resecti*** for Large Bowel malignancy
10 Minimal Access Surgery for Rectal Cancer
11 Postoperative Adjuvant Combined Modality Therapy
12 Follow-up After Potentially Curative Therapy for Rectal Cancer
13 Surgical Approach to Locally Recurrent Disease
14 Metastic Rectal Cancer
15 Rare Histiotypes
16 Quality of Life and Palliative Care in Rectal Cancer Patients
17 Costs of Rectal Cancer Patient Management
Index
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书籍介绍
Modern Management of Cancer of the Rectum is intended to provide a comprehensive overview of all ***ects of rectal neoplasms. It addresses such topics as epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and trans*** endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; togethe***ith new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.
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